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Genetic evolution of uveal melanoma guides the development of an inflammatory microenvironment

Uveal melanoma (UM) is characterized by a number of genetic aberrations that follow a certain chronology and are tightly linked to tumor recurrence and survival. Loss of chromosome 3, bi-allelic loss of BAP1 expression, and gain in chromosome 8q have been associated with metastasis formation and dea...

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Detalles Bibliográficos
Autores principales: Gezgin, Gülçin, Dogrusöz, Mehmet, van Essen, T. Huibertus, Kroes, Wilhelmina G. M., Luyten, Gregorius P. M., van der Velden, Pieter A., Walter, Vonn, Verdijk, Robert M., van Hall, Thorbald, van der Burg, Sjoerd H., Jager, Martine J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489616/
https://www.ncbi.nlm.nih.gov/pubmed/28391358
http://dx.doi.org/10.1007/s00262-017-1991-1