A framework for the use of single-chemical transcriptomics data in predicting the hazards associated with complex mixtures of polycyclic aromatic hydrocarbons

The assumption of additivity applied in the risk assessment of environmental mixtures containing carcinogenic polycyclic aromatic hydrocarbons (PAHs) was investigated using transcriptomics. MutaTMMouse were gavaged for 28 days with three doses of eight individual PAHs, two defined mixtures of PAHs,...

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Detalles Bibliográficos
Autores principales: Labib, Sarah, Williams, Andrew, Kuo, Byron, Yauk, Carole L., White, Paul A., Halappanavar, Sabina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Regulatory Toxicology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489644/
https://www.ncbi.nlm.nih.gov/pubmed/27858113
http://dx.doi.org/10.1007/s00204-016-1891-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489644/
https://www.ncbi.nlm.nih.gov/pubmed/27858113
http://dx.doi.org/10.1007/s00204-016-1891-8

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