Cyclin dependent kinase 4 and 6 inhibitors as novel therapeutic agents for targeted treatment of malignant mesothelioma

Malignant Mesothelioma (MM) is a rare and aggressive form of tumour that affects the lining of the internal organs for which current treatments have not been proven to be very effective. P16(INK4A) tumour suppressor encoding CDKN2A gene is often downregulated in MM. This protein is a cyclin dependen...

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Detalles Bibliográficos
Autores principales: Sobhani, Navid, Corona, Silvia P., Zanconati, Fabrizio, Generali, Daniele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489646/
https://www.ncbi.nlm.nih.gov/pubmed/28680533
http://dx.doi.org/10.18632/genesandcancer.138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489646/
https://www.ncbi.nlm.nih.gov/pubmed/28680533
http://dx.doi.org/10.18632/genesandcancer.138

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