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Cyclin dependent kinase 4 and 6 inhibitors as novel therapeutic agents for targeted treatment of malignant mesothelioma
Malignant Mesothelioma (MM) is a rare and aggressive form of tumour that affects the lining of the internal organs for which current treatments have not been proven to be very effective. P16(INK4A) tumour suppressor encoding CDKN2A gene is often downregulated in MM. This protein is a cyclin dependen...
Autores principales: | Sobhani, Navid, Corona, Silvia P., Zanconati, Fabrizio, Generali, Daniele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489646/ https://www.ncbi.nlm.nih.gov/pubmed/28680533 http://dx.doi.org/10.18632/genesandcancer.138 |
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