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Differential Antagonism of Human Innate Immune Responses by Tick-Borne Phlebovirus Nonstructural Proteins

In recent years, several newly discovered tick-borne viruses causing a wide spectrum of diseases in humans have been ascribed to the Phlebovirus genus of the Bunyaviridae family. The nonstructural protein (NSs) of bunyaviruses is the main virulence factor and interferon (IFN) antagonist. We studied...

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Detalles Bibliográficos
Autores principales: Rezelj, Veronica V., Li, Ping, Chaudhary, Vidyanath, Elliott, Richard M., Jin, Dong-Yan, Brennan, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489658/
https://www.ncbi.nlm.nih.gov/pubmed/28680969
http://dx.doi.org/10.1128/mSphere.00234-17