Early-Life Exposure to Lead Induces Cognitive Impairment in Elder Mice Targeting SIRT1 Phosphorylation and Oxidative Alterations

Pb is a potential risk factor for cognition, mainly mediated by enhanced oxidative stress. Resveratrol, a natural polyphenol with crucial anti-oxidative property, is recently implicated in preventing cognitive deficits in normal aging and neurodegenerative disorders. Its beneficial effects have been...

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Detalles Bibliográficos
Autores principales: Zhang, Lijie, Tu, Runqi, Wang, Yawei, Hu, Yazhen, Li, Xing, Cheng, Xuemin, Yin, Yanyan, Li, Wenjie, Huang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489681/
https://www.ncbi.nlm.nih.gov/pubmed/28706491
http://dx.doi.org/10.3389/fphys.2017.00446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489681/
https://www.ncbi.nlm.nih.gov/pubmed/28706491
http://dx.doi.org/10.3389/fphys.2017.00446

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