MicroRNA-34a dependent regulation of AXL controls the activation of dendritic cells in inflammatory arthritis

Current treatments for rheumatoid arthritis (RA) do not reverse underlying aberrant immune function. A genetic predisposition to RA, such as HLA-DR4 positivity, indicates that dendritic cells (DC) are of crucial importance to pathogenesis by activating auto-reactive lymphocytes. Here we show that mi...

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Detalles Bibliográficos
Autores principales: Kurowska-Stolarska, Mariola, Alivernini, Stefano, Melchor, Emma Garcia, Elmesmari, Aziza, Tolusso, Barbara, Tange, Clare, Petricca, Luca, Gilchrist, Derek S., Di Sante, Gabriele, Keijzer, Chantal, Stewart, Lynn, Di Mario, Clara, Morrison, Vicky, Brewer, James M., Porter, Duncan, Milling, Simon, Baxter, Ronald D., McCarey, David, Gremese, Elisa, Lemke, Greg, Ferraccioli, Gianfranco, McSharry, Charles, McInnes, Iain B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489689/
https://www.ncbi.nlm.nih.gov/pubmed/28639625
http://dx.doi.org/10.1038/ncomms15877

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489689/
https://www.ncbi.nlm.nih.gov/pubmed/28639625
http://dx.doi.org/10.1038/ncomms15877

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