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Protective effect of ginsenosides Rk3 and Rh4 on cisplatin-induced acute kidney injury in vitro and in vivo

BACKGROUND: Nephrotoxicity is the major side effect in cisplatin chemotherapy. Previously, we reported that the ginsenosides Rk3 and Rh4 reduced cisplatin toxicity on porcine renal proximal epithelial tubular cells (LLC-PK1). Here, we aimed to evaluate the protective effect of ginsenosides Rk3 and R...

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Detalles Bibliográficos
Autores principales: Baek, Seung-Hoon, Shin, Byong-kyu, Kim, Nam Jae, Chang, Sun-Young, Park, Jeong Hill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489750/
https://www.ncbi.nlm.nih.gov/pubmed/28701862
http://dx.doi.org/10.1016/j.jgr.2016.03.008