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20S-Protopanaxadiol, an aglycosylated ginsenoside metabolite, induces hepatic stellate cell apoptosis through liver kinase B1–AMP-activated protein kinase activation

BACKGROUND: Previously, we reported that Korean Red Ginseng inhibited liver fibrosis in mice and reduced the expressions of fibrogenic genes in hepatic stellate cells (HSCs). The present study was undertaken to identify the major ginsenoside responsible for reducing the numbers of HSCs and the under...

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Detalles Bibliográficos
Autores principales: Park, Sang Mi, Jung, Eun Hye, Kim, Jae Kwang, Jegal, Kyung Hwan, Park, Chung A, Cho, Il Je, Kim, Sang Chan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489770/
https://www.ncbi.nlm.nih.gov/pubmed/28701883
http://dx.doi.org/10.1016/j.jgr.2017.01.012