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A Comprehensive Guide for Performing Sample Preparation and Top-Down Protein Analysis

Methodologies for the global analysis of proteins in a sample, or proteome analysis, have been available since 1975 when Patrick O′Farrell published the first paper describing two-dimensional gel electrophoresis (2D-PAGE). This technique allowed the resolution of single protein isoforms, or proteofo...

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Detalles Bibliográficos
Autores principales: Padula, Matthew P., Berry, Iain J., O′Rourke, Matthew B., Raymond, Benjamin B.A., Santos, Jerran, Djordjevic, Steven P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489772/
https://www.ncbi.nlm.nih.gov/pubmed/28387712
http://dx.doi.org/10.3390/proteomes5020011