Glycosylated Triterpenoids as Endosomal Escape Enhancers in Targeted Tumor Therapies

Protein-based targeted toxins play an increasingly important role in targeted tumor therapies. In spite of their high intrinsic toxicity, their efficacy in animal models is low. A major reason for this is the limited entry of the toxin into the cytosol of the target cell, which is required to mediat...

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Detalles Bibliográficos
Autores principales: Fuchs, Hendrik, Niesler, Nicole, Trautner, Alexandra, Sama, Simko, Jerz, Gerold, Panjideh, Hossein, Weng, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489800/
https://www.ncbi.nlm.nih.gov/pubmed/28536357
http://dx.doi.org/10.3390/biomedicines5020014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489800/
https://www.ncbi.nlm.nih.gov/pubmed/28536357
http://dx.doi.org/10.3390/biomedicines5020014

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