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The In Vitro–In Vivo Safety Confirmation of PEG-40 Hydrogenated Castor Oil as a Surfactant for Oral Nanoemulsion Formulation

Evaluation on the safety use of high concentration of polyoxyl 40 (PEG-40) hydrogenated castor oil as a surfactant for oral nanoemulsion was performed in Webster mice. As previously reported, nearly 20% of PEG-40 hydrogenated castor oil was used to emulsify the glyceryl monooleate (GMO) as an oil to...

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Detalles Bibliográficos
Autores principales: Rachmawati, Heni, Novel, Miranti Anggraeni, Ayu, Sri, Berlian, Guntur, Tandrasasmita, Olivia Mayasari, Tjandrawinata, Raymond Rubianto, Anggadiredja, Kusnandar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489922/
https://www.ncbi.nlm.nih.gov/pubmed/28362322
http://dx.doi.org/10.3390/scipharm85020018