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The In Vitro–In Vivo Safety Confirmation of PEG-40 Hydrogenated Castor Oil as a Surfactant for Oral Nanoemulsion Formulation
Evaluation on the safety use of high concentration of polyoxyl 40 (PEG-40) hydrogenated castor oil as a surfactant for oral nanoemulsion was performed in Webster mice. As previously reported, nearly 20% of PEG-40 hydrogenated castor oil was used to emulsify the glyceryl monooleate (GMO) as an oil to...
Autores principales: | Rachmawati, Heni, Novel, Miranti Anggraeni, Ayu, Sri, Berlian, Guntur, Tandrasasmita, Olivia Mayasari, Tjandrawinata, Raymond Rubianto, Anggadiredja, Kusnandar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489922/ https://www.ncbi.nlm.nih.gov/pubmed/28362322 http://dx.doi.org/10.3390/scipharm85020018 |
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