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Low-volume resuscitation with normal saline is associated with microvascular endothelial dysfunction after hemorrhage in rats, compared to colloids and balanced crystalloids

BACKGROUND: Restoration of endothelial glycocalyx (EG) barrier may be an essential therapeutic target for successful resuscitation. The aim of this study was to compare in vivo the effects of resuscitation with normal saline (NS) to lactated Ringer’s solution (LR), 5% albumin and fresh frozen plasma...

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Detalles Bibliográficos
Autores principales: Torres, Luciana N., Chung, Kevin K., Salgado, Christi L., Dubick, Michael A., Torres Filho, Ivo P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490091/
https://www.ncbi.nlm.nih.gov/pubmed/28659186
http://dx.doi.org/10.1186/s13054-017-1745-7