ISOWN: accurate somatic mutation identification in the absence of normal tissue controls

BACKGROUND: A key step in cancer genome analysis is the identification of somatic mutations in the tumor. This is typically done by comparing the genome of the tumor to the reference genome sequence derived from a normal tissue taken from the same donor. However, there are a variety of common scenar...

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Detalles Bibliográficos
Autores principales: Kalatskaya, Irina, Trinh, Quang M., Spears, Melanie, McPherson, John D., Bartlett, John M. S., Stein, Lincoln
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490163/
https://www.ncbi.nlm.nih.gov/pubmed/28659176
http://dx.doi.org/10.1186/s13073-017-0446-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490163/
https://www.ncbi.nlm.nih.gov/pubmed/28659176
http://dx.doi.org/10.1186/s13073-017-0446-9

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