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ISOWN: accurate somatic mutation identification in the absence of normal tissue controls
BACKGROUND: A key step in cancer genome analysis is the identification of somatic mutations in the tumor. This is typically done by comparing the genome of the tumor to the reference genome sequence derived from a normal tissue taken from the same donor. However, there are a variety of common scenar...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490163/ https://www.ncbi.nlm.nih.gov/pubmed/28659176 http://dx.doi.org/10.1186/s13073-017-0446-9 |