Azithromycin decreases NALP3 mRNA stability in monocytes to limit inflammasome-dependent inflammation

BACKGROUND: Azithromycin, an antibiotic used for multiple infectious disorders, exhibits anti-inflammatory effects, but the molecular basis for this activity is not well characterized. Azithromycin inhibits IL-1β-mediated inflammation that is dependent, in part, on inflammasome activity. Here, we in...

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Detalles Bibliográficos
Autores principales: Lendermon, Elizabeth A., Coon, Tiffany A., Bednash, Joseph S., Weathington, Nathaniel M., McDyer, John F., Mallampalli, Rama K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490165/
https://www.ncbi.nlm.nih.gov/pubmed/28659178
http://dx.doi.org/10.1186/s12931-017-0608-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490165/
https://www.ncbi.nlm.nih.gov/pubmed/28659178
http://dx.doi.org/10.1186/s12931-017-0608-8

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