Cargando…

Azithromycin decreases NALP3 mRNA stability in monocytes to limit inflammasome-dependent inflammation

BACKGROUND: Azithromycin, an antibiotic used for multiple infectious disorders, exhibits anti-inflammatory effects, but the molecular basis for this activity is not well characterized. Azithromycin inhibits IL-1β-mediated inflammation that is dependent, in part, on inflammasome activity. Here, we in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lendermon, Elizabeth A., Coon, Tiffany A., Bednash, Joseph S., Weathington, Nathaniel M., McDyer, John F., Mallampalli, Rama K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490165/ https://www.ncbi.nlm.nih.gov/pubmed/28659178 http://dx.doi.org/10.1186/s12931-017-0608-8

Ejemplares similares

Targeting the deubiquitinase STAMBP inhibits NALP7 inflammasome activity
por: Bednash, Joseph S., et al.
Publicado: (2017)

Glyburide inhibits the Cryopyrin/Nalp3 inflammasome
por: Lamkanfi, Mohamed, et al.
Publicado: (2009)

Ricin Toxin Activates the NALP3 Inflammasome
por: Lindauer, Meghan, et al.
Publicado: (2010)

Malarial Hemozoin Is a Nalp3 Inflammasome Activating Danger Signal
por: Dostert, Catherine, et al.
Publicado: (2009)

The NALP3/Cryopyrin-Inflammasome Complex is Expressed in LPS-Induced Ocular Inflammation
por: González-Benítez, José F., et al.
Publicado: (2008)

The NALP3 inflammasome is involved in neurotoxic prion peptide-induced microglial activation
por: Shi, Fushan, et al.
Publicado: (2012)

Inflammasome-Independent NALP3 Contributes to High-Salt Induced Endothelial Dysfunction
por: Fu, Hui, et al.
Publicado: (2018)

NALP3-Inflammasome-Related Gene Polymorphisms in Patients with Prehypertension and Coronary Atherosclerosis
por: Zhao, Xin, et al.
Publicado: (2016)

GENETIC VARIATIONS IN NALP1 MRNA EXPRESSIONS IN HUMAN VITILIGO
por: Deo, Sudha S, et al.
Publicado: (2011)

Common Genetic Variations in the NALP3 Inflammasome Are Associated with Delayed Apoptosis of Human Neutrophils
por: Blomgran, Robert, et al.
Publicado: (2012)

The NALP3/NLRP3 Inflammasome Instigates Obesity-Induced Autoinflammation and Insulin Resistance
por: Vandanmagsar, Bolormaa, et al.
Publicado: (2011)

Mechanisims of asthma and allergic disease – 1081. Resolvin inhibits the cryopyrin/nalp3 inflammasome
por: Ruan, Cox, et al.
Publicado: (2013)

Chrysophanol Inhibits NALP3 Inflammasome Activation and Ameliorates Cerebral Ischemia/Reperfusion in Mice
por: Zhang, Nan, et al.
Publicado: (2014)

Expression of dectin-1 and enhanced activation of NALP3 inflammasome are associated with resistance to paracoccidioidomycosis
por: Feriotti, Claudia, et al.
Publicado: (2015)

CASPorter: A Novel Inducible Human CASP1/NALP3/ASC Inflammasome Biosensor
por: Zou, Chan, et al.
Publicado: (2022)

Sertoli cells have a functional NALP3 inflammasome that can modulate autophagy and cytokine production
por: Hayrabedyan, Soren, et al.
Publicado: (2016)

The Overexpression of NALP3 Inflammasome in Knee Osteoarthritis Is Associated with Synovial Membrane Prolidase and NADPH Oxidase 2
por: Clavijo-Cornejo, Denise, et al.
Publicado: (2016)

Rhein attenuates inflammation through inhibition of NF-κB and NALP3 inflammasome in vivo and in vitro
por: Ge, Hui, et al.
Publicado: (2017)

AEG-1 aggravates inflammation via promoting NALP3 inflammasome formation in murine endometriosis lesions
por: Zhao, Juan, et al.
Publicado: (2019)

Autophagy proteins regulate innate immune response by inhibiting NALP3 inflammasome-mediated mitochondrial DNA release
por: Nakahira, Kiichi, et al.
Publicado: (2010)

Corrigendum to “The Overexpression of NALP3 Inflammasome in Knee Osteoarthritis Is Associated with Synovial Membrane Prolidase and NADPH Oxidase 2”
por: Clavijo-Cornejo, Denise, et al.
Publicado: (2017)

The deubiquitinase USP13 stabilizes the anti-inflammatory receptor IL-1R8/Sigirr to suppress lung inflammation
por: Li, Lian, et al.
Publicado: (2019)

NALP3 inflammasome up-regulation and CASP1 cleavage of the glucocorticoid receptor causes glucocorticoid resistance in leukemia cells
por: Paugh, Steven W., et al.
Publicado: (2015)

The Relationship between NALP3 and Autoinflammatory Syndromes
por: Campbell, Lorna, et al.
Publicado: (2016)

NADPH Oxidase-Induced NALP3 Inflammasome Activation Is Driven by Thioredoxin-Interacting Protein Which Contributes to Podocyte Injury in Hyperglycemia
por: Gao, Pan, et al.
Publicado: (2015)

SOCS-1 Suppresses Inflammation Through Inhibition of NALP3 Inflammasome Formation in Smoke Inhalation-Induced Acute Lung Injury
por: Zhang, Leifang, et al.
Publicado: (2018)

Erratum to “NADPH Oxidase-Induced NALP3 Inflammasome Activation Is Driven by Thioredoxin-Interacting Protein Which Contributes to Podocyte Injury in Hyperglycemia”
por: Gao, Pan, et al.
Publicado: (2016)

Innate Immune Sensing of Modified Vaccinia Virus Ankara (MVA) Is Mediated by TLR2-TLR6, MDA-5 and the NALP3 Inflammasome
por: Delaloye, Julie, et al.
Publicado: (2009)

A Role for Uric Acid and the Nalp3 Inflammasome in Antiphospholipid Antibody-Induced IL-1β Production by Human First Trimester Trophoblast
por: Mulla, Melissa J., et al.
Publicado: (2013)

Human periodontal ligament stem cells secretome from multiple sclerosis patients suppresses NALP3 inflammasome activation in experimental autoimmune encephalomyelitis
por: Soundara Rajan, Thangavelu, et al.
Publicado: (2017)

Rab GTPase Mediating Regulation of NALP3 in Colorectal Cancer
por: Tezcan, Gülçin, et al.
Publicado: (2020)

Mice with miR-146a deficiency develop severe gouty arthritis via dysregulation of TRAF 6, IRAK 1 and NALP3 inflammasome
por: Zhang, Quan-Bo, et al.
Publicado: (2018)

Retraction: Innate Immune Sensing of Modified Vaccinia Virus Ankara (MVA) Is Mediated by TLR2-TLR6, MDA-5 and the NALP3 Inflammasome
Publicado: (2022)

Knockdown of MVK does not lead to changes in NALP3 expression or activation
por: Celsi, Fulvio, et al.
Publicado: (2015)

Total saponin of Dioscorea collettii attenuates MSU crystal-induced inflammation via inhibiting the activation of the NALP3 inflammasome and caspase-1 in THP-1 macrophages
por: Wang, Lu, et al.
Publicado: (2020)

F box protein FBXL2 exerts human lung tumor suppressor-like activity by ubiquitin-mediated degradation of cyclin D3 resulting in cell cycle arrest
por: Chen, Bill B., et al.
Publicado: (2011)

APO-9′-Fucoxanthinone Extracted from Undariopsis peteseniana Protects Oxidative Stress-Mediated Apoptosis in Cigarette Smoke-Exposed Human Airway Epithelial Cells
por: Jang, Jun-Ho, et al.
Publicado: (2016)

Azithromycin inhibits IL-1 secretion and non-canonical inflammasome activation
por: Gualdoni, Guido A., et al.
Publicado: (2015)

Interstrain Cooperation in Meningococcal Biofilms: Role of Autotransporters NalP and AutA
por: Pérez-Ortega, Jesús, et al.
Publicado: (2017)

Curcumin ameliorates neuropathic pain by down-regulating spinal IL-1β via suppressing astroglial NALP1 inflammasome and JAK2-STAT3 signalling
por: Liu, Shenbin, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_ukehn43c9q9sgoh9oisuplb71m