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ZNF300 tight self-regulation and functioning through DNA methylation and histone acetylation

BACKGROUND: Accumulating evidence demonstrates that the KRAB-ZNFs involve in various biological processes. As a typical member of KRAB-ZNFs, dysregulation of ZNF300 contributes to multiple pathologies such as leukemia and cancer. However, mechanisms underlying ZNF300 tight regulation and its pathoph...

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Detalles Bibliográficos
Autores principales: Yan, Feng-Juan, Fan, Jingyi, Huang, Zan, Zhang, Jun-Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490171/
https://www.ncbi.nlm.nih.gov/pubmed/28670441
http://dx.doi.org/10.1186/s13578-017-0160-8