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A practical and catalyst-free trifluoroethylation reaction of amines using trifluoroacetic acid
Amines are a fundamentally important class of biologically active compounds and the ability to manipulate their physicochemical properties through the introduction of fluorine is of paramount importance in medicinal chemistry. Current synthesis methods for the construction of fluorinated amines rely...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490195/ https://www.ncbi.nlm.nih.gov/pubmed/28649981 http://dx.doi.org/10.1038/ncomms15913 |