Structural and regulatory diversity shape HLA-C protein expression levels

Expression of HLA-C varies widely across individuals in an allele-specific manner. This variation in expression can influence efficacy of the immune response, as shown for infectious and autoimmune diseases. MicroRNA binding partially influences differential HLA-C expression, but the additional cont...

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Detalles Bibliográficos
Autores principales: Kaur, Gurman, Gras, Stephanie, Mobbs, Jesse I., Vivian, Julian P., Cortes, Adrian, Barber, Thomas, Kuttikkatte, Subita Balaram, Jensen, Lise Torp, Attfield, Kathrine E., Dendrou, Calliope A., Carrington, Mary, McVean, Gil, Purcell, Anthony W., Rossjohn, Jamie, Fugger, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490200/
https://www.ncbi.nlm.nih.gov/pubmed/28649982
http://dx.doi.org/10.1038/ncomms15924

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490200/
https://www.ncbi.nlm.nih.gov/pubmed/28649982
http://dx.doi.org/10.1038/ncomms15924

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