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Structural and regulatory diversity shape HLA-C protein expression levels
Expression of HLA-C varies widely across individuals in an allele-specific manner. This variation in expression can influence efficacy of the immune response, as shown for infectious and autoimmune diseases. MicroRNA binding partially influences differential HLA-C expression, but the additional cont...
Autores principales: | Kaur, Gurman, Gras, Stephanie, Mobbs, Jesse I., Vivian, Julian P., Cortes, Adrian, Barber, Thomas, Kuttikkatte, Subita Balaram, Jensen, Lise Torp, Attfield, Kathrine E., Dendrou, Calliope A., Carrington, Mary, McVean, Gil, Purcell, Anthony W., Rossjohn, Jamie, Fugger, Lars |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490200/ https://www.ncbi.nlm.nih.gov/pubmed/28649982 http://dx.doi.org/10.1038/ncomms15924 |
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