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Targeting MCL-1 sensitizes human esophageal squamous cell carcinoma cells to cisplatin-induced apoptosis

BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is one of the most lethal malignancies in China and is an exceptionally drug-resistant tumor with a 5-year survival rate less than 15%. Cisplatin is the most commonly used conventional chemotherapeutic drug for the treatment of ESCC, but some pat...

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Detalles Bibliográficos
Autores principales: Yu, Xinfang, Li, Wei, Xia, Zhenkun, Xie, Li, Ma, Xiaolong, Liang, Qi, Liu, Lijun, Wang, Jian, Zhou, Xinmin, Yang, Yifeng, Liu, Haidan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490225/
https://www.ncbi.nlm.nih.gov/pubmed/28659182
http://dx.doi.org/10.1186/s12885-017-3442-y