Cargando…
Targeting MCL-1 sensitizes human esophageal squamous cell carcinoma cells to cisplatin-induced apoptosis
BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is one of the most lethal malignancies in China and is an exceptionally drug-resistant tumor with a 5-year survival rate less than 15%. Cisplatin is the most commonly used conventional chemotherapeutic drug for the treatment of ESCC, but some pat...
Autores principales: | Yu, Xinfang, Li, Wei, Xia, Zhenkun, Xie, Li, Ma, Xiaolong, Liang, Qi, Liu, Lijun, Wang, Jian, Zhou, Xinmin, Yang, Yifeng, Liu, Haidan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490225/ https://www.ncbi.nlm.nih.gov/pubmed/28659182 http://dx.doi.org/10.1186/s12885-017-3442-y |
Ejemplares similares
-
Regulation of Mcl-1 by constitutive activation of NF-kappaB contributes to cell viability in human esophageal squamous cell carcinoma cells
por: Liu, Haidan, et al.
Publicado: (2014) -
EZH2-mediated Puma gene repression regulates non-small cell lung cancer cell proliferation and cisplatin-induced apoptosis
por: Liu, Haidan, et al.
Publicado: (2016) -
Repression of Noxa by Bmi1 contributes to deguelin‐induced apoptosis in non‐small cell lung cancer cells
por: Li, Wei, et al.
Publicado: (2018) -
Skp2 stabilizes Mcl-1 and confers radioresistance in colorectal cancer
por: Yu, Xinfang, et al.
Publicado: (2022) -
Deguelin, an Aurora B Kinase Inhibitor, Exhibits Potent Anti-Tumor Effect in Human Esophageal Squamous Cell Carcinoma
por: Yu, Xinfang, et al.
Publicado: (2017)