The structural and functional characterization of human RecQ4 reveals insights into its helicase mechanism

RecQ4 is a member of the RecQ helicase family, an evolutionarily conserved class of enzymes, dedicated to preserving genomic integrity by operating in telomere maintenance, DNA repair and replication. While reduced RecQ4 activity is associated with cancer predisposition and premature aging, RecQ4 up...

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Detalles Bibliográficos
Autores principales: Kaiser, Sebastian, Sauer, Florian, Kisker, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490261/
https://www.ncbi.nlm.nih.gov/pubmed/28653661
http://dx.doi.org/10.1038/ncomms15907

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490261/
https://www.ncbi.nlm.nih.gov/pubmed/28653661
http://dx.doi.org/10.1038/ncomms15907

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