Prolastin, a pharmaceutical preparation of purified human α1-antitrypsin, blocks endotoxin-mediated cytokine release

BACKGROUND: α1-antitrypsin (AAT) serves primarily as an inhibitor of the elastin degrading proteases, neutrophil elastase and proteinase 3. There is ample clinical evidence that inherited severe AAT deficiency predisposes to chronic obstructive pulmonary disease. Augmentation therapy for AAT deficie...

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Detalles Bibliográficos
Autores principales: Nita, Izabela, Hollander, Camilla, Westin, Ulla, Janciauskiene, Sabina-Marija
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549028/
https://www.ncbi.nlm.nih.gov/pubmed/15683545
http://dx.doi.org/10.1186/1465-9921-6-12

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549028/
https://www.ncbi.nlm.nih.gov/pubmed/15683545
http://dx.doi.org/10.1186/1465-9921-6-12

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