Pupillary Light Reflexes in Severe Photoreceptor Blindness Isolate the Melanopic Component of Intrinsically Photosensitive Retinal Ganglion Cells

PURPOSE: Pupillary light reflex (PLR) is driven by outer retinal photoreceptors and by melanopsin-expressing intrinsically photosensitive retinal ganglion cells of the inner retina. To isolate the melanopic component, we studied patients with severe vision loss due to Leber congenital amaurosis (LCA...

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Detalles Bibliográficos
Autores principales: Charng, Jason, Jacobson, Samuel G., Heon, Elise, Roman, Alejandro J., McGuigan, David B., Sheplock, Rebecca, Kosyk, Mychajlo S., Swider, Malgorzata, Cideciyan, Artur V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2017
Materias:
Retina
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490362/
https://www.ncbi.nlm.nih.gov/pubmed/28660274
http://dx.doi.org/10.1167/iovs.17-21909

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490362/
https://www.ncbi.nlm.nih.gov/pubmed/28660274
http://dx.doi.org/10.1167/iovs.17-21909

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