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Development of a Glycosaminoglycan Derived, Selectin Targeting Anti-Adhesive Coating to Treat Endothelial Cell Dysfunction

Endothelial cell (EC) dysfunction is associated with many disease states including deep vein thrombosis (DVT), chronic kidney disease, sepsis and diabetes. Loss of the glycocalyx, a thin glycosaminoglycan (GAG)-rich layer on the EC surface, is a key feature of endothelial dysfunction and increases e...

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Detalles Bibliográficos
Autores principales: Wodicka, James R., Chambers, Andrea M., Sangha, Gurneet S., Goergen, Craig J., Panitch, Alyssa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490393/
https://www.ncbi.nlm.nih.gov/pubmed/28353658
http://dx.doi.org/10.3390/ph10020036