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Syntheses of Radioiodinated Pyrimidine-2,4,6-Triones as Potential Agents for Non-Invasive Imaging of Matrix Metalloproteinases

Dysregulated expression or activation of matrix metalloproteinases (MMPs) is observed in many kinds of live-threatening diseases. Therefore, MMP imaging for example with radiolabelled MMP inhibitors (MMPIs) potentially represents a valuable tool for clinical diagnostics using non-invasive single pho...

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Detalles Bibliográficos
Autores principales: Breyholz, Hans-Jörg, Kopka, Klaus, Schäfers, Michael, Wagner, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490406/
https://www.ncbi.nlm.nih.gov/pubmed/28556793
http://dx.doi.org/10.3390/ph10020049