Chiral Derivatives of Xanthones: Investigation of the Effect of Enantioselectivity on Inhibition of Cyclooxygenases (COX-1 and COX-2) and Binding Interaction with Human Serum Albumin

Searching of new enantiomerically pure chiral derivatives of xanthones (CDXs) with potential pharmacological properties, particularly those with anti-inflammatory activity, has remained an area of interest of our group. Herein, we describe in silico studies and in vitro inhibitory assays of cyclooxy...

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Detalles Bibliográficos
Autores principales: Fernandes, Carla, Palmeira, Andreia, Ramos, Inês I., Carneiro, Carlos, Afonso, Carlos, Tiritan, Maria Elizabeth, Cidade, Honorina, Pinto, Paula C.A.G., Saraiva, M. Lúcia M.F.S., Reis, Salette, Pinto, Madalena M.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490407/
https://www.ncbi.nlm.nih.gov/pubmed/28561772
http://dx.doi.org/10.3390/ph10020050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490407/
https://www.ncbi.nlm.nih.gov/pubmed/28561772
http://dx.doi.org/10.3390/ph10020050

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