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Ratiometric detection of pH fluctuation in mitochondria with a new fluorescein/cyanine hybrid sensor

The homeostasis of mitochondrial pH (pH(m)) is crucial in cell physiology. Developing small-molecular fluorescent sensors for the ratiometric detection of pH(m) fluctuation is highly demanded yet challenging. A ratiometric pH sensor, Mito-pH, was constructed by integrating a pH-sensitive FITC fluoro...

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Detalles Bibliográficos
Autores principales: Chen, Yuncong, Zhu, Chengcheng, Cen, Jiajie, Bai, Yang, He, Weijiang, Guo, Zijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490428/
https://www.ncbi.nlm.nih.gov/pubmed/28706690
http://dx.doi.org/10.1039/c4sc04021j