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Abnormalities in alternative splicing of angiogenesis-related genes and their role in HIV-related cancers

Alternative splicing of mRNA leads to an increase in proteome biodiversity by allowing the generation of multiple mRNAs, coding for multiple protein isoforms of various structural and functional properties from a single primary pre-mRNA transcript. The protein isoforms produced are tightly regulated...

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Detalles Bibliográficos
Autores principales: Mthembu, Nonkululeko N, Mbita, Zukile, Hull, Rodney, Dlamini, Zodwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490432/
https://www.ncbi.nlm.nih.gov/pubmed/28694706
http://dx.doi.org/10.2147/HIV.S124911