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Abnormalities in alternative splicing of angiogenesis-related genes and their role in HIV-related cancers
Alternative splicing of mRNA leads to an increase in proteome biodiversity by allowing the generation of multiple mRNAs, coding for multiple protein isoforms of various structural and functional properties from a single primary pre-mRNA transcript. The protein isoforms produced are tightly regulated...
Autores principales: | Mthembu, Nonkululeko N, Mbita, Zukile, Hull, Rodney, Dlamini, Zodwa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490432/ https://www.ncbi.nlm.nih.gov/pubmed/28694706 http://dx.doi.org/10.2147/HIV.S124911 |
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