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Signalling crosstalk in FGF2-mediated protection of endothelial cells from HIV-gp120

BACKGROUND: The blood brain barrier (BBB) is the first line of defence of the central nervous system (CNS) against circulating pathogens, such as HIV. The cytotoxic HIV protein, gp120, damages endothelial cells of the BBB, thereby compromising its integrity, which may lead to migration of HIV-infect...

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Detalles Bibliográficos
Autores principales: Langford, Dianne, Hurford, Rosemary, Hashimoto, Makoto, Digicaylioglu, Murat, Masliah, Eliezer
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549045/
https://www.ncbi.nlm.nih.gov/pubmed/15689238
http://dx.doi.org/10.1186/1471-2202-6-8