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Interactions between xenoestrogens and ketoconazole on hepatic CYP1A and CYP3A, in juvenile Atlantic cod (Gadus morhua)

BACKGROUND: Xenoestrogens and antifungal azoles probably share a common route of metabolism, through hepatic cytochrome P450 (CYP) enzymes. Chemical interactions with metabolic pathways may affect clearance of both xenobiotics and endobiotics. This study was carried out to identify possible chemical...

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Detalles Bibliográficos
Autores principales: Hasselberg, Linda, Grøsvik, Bjørn E, Goksøyr, Anders, Celander, Malin C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549046/
https://www.ncbi.nlm.nih.gov/pubmed/15701172
http://dx.doi.org/10.1186/1476-5926-4-2