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Osthole Enhances Osteogenesis in Osteoblasts by Elevating Transcription Factor Osterix via cAMP/CREB Signaling In Vitro and In Vivo

Anabolic anti-osteoporotic agents are desirable for treatment and prevention of osteoporosis and fragility fractures. Osthole is a coumarin derivative extracted from the medicinal herbs Cnidium monnieri (L.) Cusson and Angelica pubescens Maxim.f. Osthole has been reported with osteogenic and anti-os...

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Detalles Bibliográficos
Autores principales: Zhang, Zhong-Rong, Leung, Wing Nang, Li, Gang, Kong, Siu Kai, Lu, Xiong, Wong, Yin Mei, Chan, Chun Wai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490567/
https://www.ncbi.nlm.nih.gov/pubmed/28629115
http://dx.doi.org/10.3390/nu9060588