Kaempherol and Luteolin Decrease Claudin-2 Expression Mediated by Inhibition of STAT3 in Lung Adenocarcinoma A549 Cells

Claudin-2 is highly expressed in human lung adenocarcinoma tissues and may be a novel target for cancer chemotherapy because knockdown of claudin-2 decreases cell proliferation. We found that flavonoids including kaempferol, chrysin, and luteolin concentration-dependently decrease claudin-2 expressi...

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Detalles Bibliográficos
Autores principales: Sonoki, Hiroyuki, Tanimae, Asami, Endo, Satoshi, Matsunaga, Toshiyuki, Furuta, Takumi, Ichihara, Kenji, Ikari, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490576/
https://www.ncbi.nlm.nih.gov/pubmed/28608828
http://dx.doi.org/10.3390/nu9060597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490576/
https://www.ncbi.nlm.nih.gov/pubmed/28608828
http://dx.doi.org/10.3390/nu9060597

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