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Kaempherol and Luteolin Decrease Claudin-2 Expression Mediated by Inhibition of STAT3 in Lung Adenocarcinoma A549 Cells
Claudin-2 is highly expressed in human lung adenocarcinoma tissues and may be a novel target for cancer chemotherapy because knockdown of claudin-2 decreases cell proliferation. We found that flavonoids including kaempferol, chrysin, and luteolin concentration-dependently decrease claudin-2 expressi...
Autores principales: | Sonoki, Hiroyuki, Tanimae, Asami, Endo, Satoshi, Matsunaga, Toshiyuki, Furuta, Takumi, Ichihara, Kenji, Ikari, Akira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490576/ https://www.ncbi.nlm.nih.gov/pubmed/28608828 http://dx.doi.org/10.3390/nu9060597 |
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