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Regulation of A disintegrin and metalloproteinase (ADAM) family sheddases ADAM10 and ADAM17: The emerging role of tetraspanins and rhomboids

A disintegrin and metalloprotease (ADAM) 10 and ADAM17 are ubiquitous transmembrane “molecular scissors” which proteolytically cleave, or shed, the extracellular regions of other transmembrane proteins. ADAM10 is essential for development because it cleaves Notch proteins to induce Notch signaling a...

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Detalles Bibliográficos
Autores principales: Matthews, Alexandra L., Noy, Peter J., Reyat, Jasmeet S., Tomlinson, Michael G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490636/
https://www.ncbi.nlm.nih.gov/pubmed/27256961
http://dx.doi.org/10.1080/09537104.2016.1184751