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Genome-scale approaches for discovering novel nonconventional splicing substrates of the Ire1 nuclease

BACKGROUND: The unfolded protein response (UPR) allows intracellular feedback regulation that adjusts the protein-folding capacity of the endoplasmic reticulum (ER) according to need. The signal from the ER lumen is transmitted by the ER-transmembrane kinase Ire1, which upon activation displays a si...

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Detalles Bibliográficos
Autores principales: Niwa, Maho, Patil, Christopher K, DeRisi, Joe, Walter, Peter
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549064/
https://www.ncbi.nlm.nih.gov/pubmed/15642095
http://dx.doi.org/10.1186/gb-2004-6-1-r3