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Genome-scale approaches for discovering novel nonconventional splicing substrates of the Ire1 nuclease
BACKGROUND: The unfolded protein response (UPR) allows intracellular feedback regulation that adjusts the protein-folding capacity of the endoplasmic reticulum (ER) according to need. The signal from the ER lumen is transmitted by the ER-transmembrane kinase Ire1, which upon activation displays a si...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549064/ https://www.ncbi.nlm.nih.gov/pubmed/15642095 http://dx.doi.org/10.1186/gb-2004-6-1-r3 |