Biophysical Mode-of-Action and Selectivity Analysis of Allosteric Inhibitors of Hepatitis C Virus (HCV) Polymerase

Allosteric inhibitors of hepatitis C virus (HCV) non-structural protein 5B (NS5B) polymerase are effective for treatment of genotype 1, although their mode of action and potential to inhibit other isolates and genotypes are not well established. We have used biophysical techniques and a novel biosen...

Descripción completa

Detalles Bibliográficos
Autores principales: Abdurakhmanov, Eldar, Øie Solbak, Sara, Danielson, U. Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490826/
https://www.ncbi.nlm.nih.gov/pubmed/28621755
http://dx.doi.org/10.3390/v9060151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490826/
https://www.ncbi.nlm.nih.gov/pubmed/28621755
http://dx.doi.org/10.3390/v9060151

Ejemplares similares