A tiling1deletion based genetic screen for cis-regulatory element identification in mammalian cells

Millions of cis-regulatory elements are predicted in the human genome, but direct evidence for their biological function is still scarce. Here we report a high-throughput method, Cis-Regulatory Element Scan by Tiling-deletion and sequencing (CREST-seq), for unbiased discovery and functional assessme...

Descripción completa

Detalles Bibliográficos
Autores principales: Diao, Yarui, Fang, Rongxin, Li, Bin, Meng, Zhipeng, Yu, Juntao, Qiu, Yunjiang, Lin, Kimberly C., Huang, Hui, Liu, Tristin, Marina, Ryan J, Jung, Inkyung, Shen, Yin, Guan, Kun-Liang, Ren, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490986/
https://www.ncbi.nlm.nih.gov/pubmed/28417999
http://dx.doi.org/10.1038/nmeth.4264

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490986/
https://www.ncbi.nlm.nih.gov/pubmed/28417999
http://dx.doi.org/10.1038/nmeth.4264

Ejemplares similares