Cargando…

A tiling1deletion based genetic screen for cis-regulatory element identification in mammalian cells

Millions of cis-regulatory elements are predicted in the human genome, but direct evidence for their biological function is still scarce. Here we report a high-throughput method, Cis-Regulatory Element Scan by Tiling-deletion and sequencing (CREST-seq), for unbiased discovery and functional assessme...

Descripción completa

Detalles Bibliográficos
Autores principales:	Diao, Yarui, Fang, Rongxin, Li, Bin, Meng, Zhipeng, Yu, Juntao, Qiu, Yunjiang, Lin, Kimberly C., Huang, Hui, Liu, Tristin, Marina, Ryan J, Jung, Inkyung, Shen, Yin, Guan, Kun-Liang, Ren, Bing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490986/ https://www.ncbi.nlm.nih.gov/pubmed/28417999 http://dx.doi.org/10.1038/nmeth.4264

Ejemplares similares

Identification of cis-Regulatory Elements in the Mammalian Genome: The cREMaG Database
por: Piechota, Marcin, et al.
Publicado: (2010)

GPMiner: an integrated system for mining combinatorial cis-regulatory elements in mammalian gene group
por: Lee, Tzong-Yi, et al.
Publicado: (2012)

Transposable elements as a potent source of diverse cis-regulatory sequences in mammalian genomes
por: Sundaram, Vasavi, et al.
Publicado: (2020)

Correlated Evolution of Positions within Mammalian cis Elements
por: Mukherjee, Rithun, et al.
Publicado: (2013)

The Cis-regulatory Logic of the Mammalian Photoreceptor Transcriptional Network
por: Hsiau, Timothy H.-C., et al.
Publicado: (2007)

Cis-regulatory landscapes in the evolution and development of the mammalian skull
por: Kaucka, Marketa
Publicado: (2023)

A new class of temporarily phenotypic enhancers identified by CRISPR/Cas9-mediated genetic screening
por: Diao, Yarui, et al.
Publicado: (2016)

A cis-regulatory module activating transcription in the suspensor contains five cis-regulatory elements
por: Henry, Kelli F., et al.
Publicado: (2015)

CEAS: cis-regulatory element annotation system
por: Ji, Xuwo, et al.
Publicado: (2006)

Redundancy and the Evolution of Cis-Regulatory Element Multiplicity
por: Paixão, Tiago, et al.
Publicado: (2010)

Epistatic Interactions in the Arabinose Cis-Regulatory Element
por: Lagator, Mato, et al.
Publicado: (2016)

Deletion Hotspots in AMACR Promoter CpG Island Are cis-Regulatory Elements Controlling the Gene Expression in the Colon
por: Zhang, Xiang, et al.
Publicado: (2009)

Novel mRNAs 3′ end-associated cis-regulatory elements with epigenomic signatures of mammalian enhancers in the Arabidopsis genome
por: Wang, Hsiao-Lin V., et al.
Publicado: (2019)

The Influence of cis-Regulatory Elements on DNA Methylation Fidelity
por: Teng, Mingxiang, et al.
Publicado: (2012)

Study of Cis-regulatory Elements in the Ascidian Ciona intestinalis
por: Irvine, Steven Q
Publicado: (2013)

Changes in Cis-regulatory Elements during Morphological Evolution
por: Gaunt, Stephen J., et al.
Publicado: (2012)

uORFs: Important Cis-Regulatory Elements in Plants
por: Zhang, Ting, et al.
Publicado: (2020)

CFTR Cooperative Cis-Regulatory Elements in Intestinal Cells
por: Collobert, Mégane, et al.
Publicado: (2021)

Mapping cis-regulatory elements in the midgestation mouse placenta
por: Starks, Rebekah R., et al.
Publicado: (2021)

PreCisIon: PREdiction of CIS-regulatory elements improved by gene’s positION
por: Elati, Mohamed, et al.
Publicado: (2013)

Massively parallel cis-regulatory analysis in the mammalian central nervous system
por: Shen, Susan Q., et al.
Publicado: (2016)

Parallel characterization of cis-regulatory elements for multiple genes using CRISPRpath
por: Ren, Xingjie, et al.
Publicado: (2021)

Exaptation of Transposable Elements into Novel Cis-Regulatory Elements: Is the Evidence Always Strong?
por: de Souza, Flávio S.J., et al.
Publicado: (2013)

Dual functionality of cis-regulatory elements as developmental enhancers and Polycomb response elements
por: Erceg, Jelena, et al.
Publicado: (2017)

Functional validation of transposable element–derived cis-regulatory elements in Atlantic salmon
por: Sahlström, Hanna M, et al.
Publicado: (2023)

Prediction of regulatory elements in mammalian genomes using chromatin signatures
por: Won, Kyoung-Jae, et al.
Publicado: (2008)

Identification of cis-Regulatory Elements in the dmyc Gene of Drosophila Melanogaster
por: Kharazmi, Jasmine, et al.
Publicado: (2011)

BLSSpeller: exhaustive comparative discovery of conserved cis-regulatory elements
por: De Witte, Dieter, et al.
Publicado: (2015)

High-throughput discovery of post-transcriptional cis-regulatory elements
por: Wissink, Erin M., et al.
Publicado: (2016)

Identification and Conservation Analysis of Cis-Regulatory Elements in Pig Liver
por: Luan, Yu, et al.
Publicado: (2019)

On the mechanistic nature of epistasis in a canonical cis-regulatory element
por: Lagator, Mato, et al.
Publicado: (2017)

Widespread Long-range Cis-Regulatory Elements in the Maize Genome
por: Ricci, William A., et al.
Publicado: (2019)

The Role of cis- and trans-Acting RNA Regulatory Elements in Leukemia
por: Elcheva, Irina A., et al.
Publicado: (2020)

Targeting Cis-Regulatory Elements for Rice Grain Quality Improvement
por: Ding, Yu, et al.
Publicado: (2021)

CRISPR Deletion of a SVA Retrotransposon Demonstrates Function as a cis-Regulatory Element at the TRPV1/TRPV3 Intergenic Region
por: Price, Emma, et al.
Publicado: (2021)

Tissue-specific regulatory elements in mammalian promoters
por: Smith, Andrew D, et al.
Publicado: (2007)

Gata2 cis-element is required for hematopoietic stem cell generation in the mammalian embryo
por: Gao, Xin, et al.
Publicado: (2013)

Shuffling of cis-regulatory elements is a pervasive feature of the vertebrate lineage
por: Sanges, Remo, et al.
Publicado: (2006)

Bounded search for de novo identification of degenerate cis-regulatory elements
por: Carlson, Jonathan M, et al.
Publicado: (2006)

jPREdictor: a versatile tool for the prediction of cis-regulatory elements
por: Fiedler, Thomas, et al.
Publicado: (2006)

Cannot write session to /tmp/vufind_sessions/sess_ah7rnbfjocubbv4i7cq3364568