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APNG as a prognostic marker in patients with glioblastoma

AIM: Expression of the base excision repair enzyme alkylpurine-DNA-N-glycosylase (APNG) has been correlated to temozolomide resistance. Our aim was to evaluate the prognostic value of APNG in a population-based cohort with 242 gliomas including 185 glioblastomas (GBMs). Cellular heterogeneity of GBM...

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Detalles Bibliográficos
Autores principales: Fosmark, Sigurd, Hellwege, Sofie, Dahlrot, Rikke H., Jensen, Kristian L., Derand, Helene, Lohse, Jesper, Sørensen, Mia D., Hansen, Steinbjørn, Kristensen, Bjarne W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490991/
https://www.ncbi.nlm.nih.gov/pubmed/28662073
http://dx.doi.org/10.1371/journal.pone.0178693