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Activation of complement factor B contributes to murine and human myocardial ischemia/reperfusion injury

The pathophysiology of myocardial injury that results from cardiac ischemia and reperfusion (I/R) is incompletely understood. Experimental evidence from murine models indicates that innate immune mechanisms including complement activation via the classical and lectin pathways are crucial. Whether fa...

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Detalles Bibliográficos
Autores principales: Chun, Nicholas, Haddadin, Ala S., Liu, Junying, Hou, Yunfang, Wong, Karen A., Lee, Daniel, Rushbrook, Julie I., Gulaya, Karan, Hines, Roberta, Hollis, Tamika, Nistal Nuno, Beatriz, Mangi, Abeel A., Hashim, Sabet, Pekna, Marcela, Catalfamo, Amy, Chin, Hsiao-ying, Patel, Foramben, Rayala, Sravani, Shevde, Ketan, Heeger, Peter S., Zhang, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491012/
https://www.ncbi.nlm.nih.gov/pubmed/28662037
http://dx.doi.org/10.1371/journal.pone.0179450