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Activation of complement factor B contributes to murine and human myocardial ischemia/reperfusion injury
The pathophysiology of myocardial injury that results from cardiac ischemia and reperfusion (I/R) is incompletely understood. Experimental evidence from murine models indicates that innate immune mechanisms including complement activation via the classical and lectin pathways are crucial. Whether fa...
Autores principales: | Chun, Nicholas, Haddadin, Ala S., Liu, Junying, Hou, Yunfang, Wong, Karen A., Lee, Daniel, Rushbrook, Julie I., Gulaya, Karan, Hines, Roberta, Hollis, Tamika, Nistal Nuno, Beatriz, Mangi, Abeel A., Hashim, Sabet, Pekna, Marcela, Catalfamo, Amy, Chin, Hsiao-ying, Patel, Foramben, Rayala, Sravani, Shevde, Ketan, Heeger, Peter S., Zhang, Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491012/ https://www.ncbi.nlm.nih.gov/pubmed/28662037 http://dx.doi.org/10.1371/journal.pone.0179450 |
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