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BKM120 induces apoptosis and inhibits tumor growth in medulloblastoma

Medulloblastoma (MB) is the most common malignant brain tumor in children, accounting for nearly 20 percent of all childhood brain tumors. New treatment strategies are needed to improve patient survival outcomes and to reduce adverse effects of current therapy. The phosphatidylinositol-3-kinase (PI3...

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Detalles Bibliográficos
Autores principales: Zhao, Ping, Hall, Jacob, Durston, Mary, Voydanoff, Austin, VanSickle, Elizabeth, Kelly, Shannon, Nagulapally, Abhinav B, Bond, Jeffery, Saulnier Sholler, Giselle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491106/
https://www.ncbi.nlm.nih.gov/pubmed/28662162
http://dx.doi.org/10.1371/journal.pone.0179948