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BKM120 induces apoptosis and inhibits tumor growth in medulloblastoma
Medulloblastoma (MB) is the most common malignant brain tumor in children, accounting for nearly 20 percent of all childhood brain tumors. New treatment strategies are needed to improve patient survival outcomes and to reduce adverse effects of current therapy. The phosphatidylinositol-3-kinase (PI3...
Autores principales: | Zhao, Ping, Hall, Jacob, Durston, Mary, Voydanoff, Austin, VanSickle, Elizabeth, Kelly, Shannon, Nagulapally, Abhinav B, Bond, Jeffery, Saulnier Sholler, Giselle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491106/ https://www.ncbi.nlm.nih.gov/pubmed/28662162 http://dx.doi.org/10.1371/journal.pone.0179948 |
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