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A new approach for the assessment of the toxicity of polyphenol-rich compounds with the use of high content screening analysis

The toxicity of in vitro tested compounds is usually evaluated based on AC(50) values calculated from dose-response curves. However, there is a large group of compounds for which a standard four-parametric sigmoid curve fitting may be inappropriate for estimating AC(50). In the present study, 22 pol...

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Detalles Bibliográficos
Autores principales: Boncler, Magdalena, Golanski, Jacek, Lukasiak, Magdalena, Redzynia, Malgorzata, Dastych, Jaroslaw, Watala, Cezary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491109/
https://www.ncbi.nlm.nih.gov/pubmed/28662177
http://dx.doi.org/10.1371/journal.pone.0180022