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Ultrasensitivity in signaling cascades revisited: Linking local and global ultrasensitivity estimations
Ultrasensitive response motifs, capable of converting graded stimuli into binary responses, are well-conserved in signal transduction networks. Although it has been shown that a cascade arrangement of multiple ultrasensitive modules can enhance the system’s ultrasensitivity, how a given combination...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491127/ https://www.ncbi.nlm.nih.gov/pubmed/28662096 http://dx.doi.org/10.1371/journal.pone.0180083 |